Malaria Control & Elimination

The increasing insecticide resistant population of A. gambiae S.l. mosquitoes in Nigeria and most of West Africa and other parts of the sub-Saharan regions of Africa is becoming worrisome and currently, it’s becoming a threat to the tools widely used for vector control. Though, resistance developed faster in most areas where pyrethroids previously, has been tried alone than those places tried with other earlier applications such as Organophosphates, Organochlorine and the Carbamates group inclusive. The higher coverage of Indoor Residual Spraying (IRS) is suggestive of effective susceptibility in vector species of Anopheles tried in Nasarawa state, Nigeria using Inesfly Carbapaint 10 (Propoxur 1.0 w/w) insecticidal paint. The wall cone bio-assay used, a primer was employed to prime a cemented plaster surface and wooden board under laboratory condition within the 24–48 hours before the paint application. The primer was allowed to get dried up within a given time frame before the Inesfly Carbapaint 10 (Propoxur 1.0% w/w) insecticidal paint was applied at the dosage of 8 m2/L for cement plaster surface and wooden board drying at room temperature for 5 consecutive days. The wall-cone bio-assay and the varied wall cemented plaster surface parameters of 0.5 ml, 1.0 m and 1.5 m and wooden board were both treated with 1.0% propoxur painted substrates in 24 hours post exposure to validate 6 months post application. The bio-efficacy and durability of indoor residual treatment with propoxur 1.0% w/w insecticidal paint from February to July, 2018 (6 months) were shaded on the primer substrate. The wild A. gambiae mosquitoes after 24 hours of observation, showed 100% knockdown/mortality at varied conebioassay wall parameters height. Monthly distribution gave susceptibility result treatment with low toxicity effect and the results presented as Mean ± standard deviations of triplicate observations (100.00 ± 0.00). From the tried result under laboratory strain condition, with increased in those risk from malaria with Indoor Residual Spraying (IRS) admixed microencapsulated insecticidal paint have proven positive result activities and broad spectrum against insects and agricultural pests with greater hope to public health and decreasing in cases of malaria transmission. Indeed, the carbamates based insecticides is on the most preferred in the fight against malaria vector as such, should further paired or synergize with other affluent pyrethroids based to intensify were possible, high level of susceptibility, knockdown, hoping that new-age additional classes of insecticides (Pyrrole and Neonicotinoid) will become available for the control of adult mosquito.

Malaria continues to be a global health challenge, affecting millions of people each year. However, advancements in research and technology have led to significant innovations in malaria management. This comprehensive guide explores the latest breakthroughs in malaria prevention, diagnosis and treatment, highlighting the promising strategies that offer hope in the fight against this deadly disease. From cutting-edge vaccines to innovative mosquito control methods, this article provides a thorough overview of the evolving landscape of malaria management. Advances in technology have led to the creation of portable, point-of-care testing devices that can diagnose malaria in remote or resource-limited areas. These devices have been crucial in improving early detection and treatment. Polymerase chain reaction (PCR) and other molecular diagnostic techniques have enhanced the accuracy of malaria diagnosis. These methods can detect low levels of parasites in the blood, aiding in the diagnosis of asymptomatic infections.

Malaria remains a global health challenge, causing immense suffering and claiming countless lives every year. Despite significant progress in recent decades, the fight against this deadly disease is far from over. This article explores the latest strategies and breakthroughs in the battle against malaria, including cutting-edge research, innovative prevention methods and the quest for an effective vaccine. By highlighting these advancements, we aim to shed light on the ongoing efforts to eradicate malaria and improve the lives of millions.

Malaria remains a global health threat, causing significant morbidity and mortality, particularly in regions with limited access to healthcare resources. Despite ongoing efforts to combat the disease, it continues to pose challenges. This article explores the latest approaches and challenges in malaria prevention and control, highlighting the importance of innovation, collaboration and community engagement. The development of a malaria vaccine has been a long-standing goal in the field. Recent breakthroughs in vaccine development have resulted in the approval of the RTS,S/AS01 malaria vaccine for use in Africa. Continued research is focused on improving vaccine efficacy and developing new vaccine candidates. Access to effective antimalarial drugs is crucial for both treatment and prevention. The emergence of drug-resistant strains of Plasmodium underscores the need for ongoing research and the development of new drug combinations to combat resistance.