Oral Health Case Reports

Microorganisms enter your body through the oral cavity, where they spread to numerous distant organs in addition to the directly related digestive and respiratory tracts. In addition to affecting the gut microbiome profile, oral microbiota that travels to the end of the intestine and circulates in our bodies through blood vessels also contribute to a number of systemic disorders. In order to emphasise the significance of the oral cavity in systemic health, we propose the important role of "leaky gum," as an analogy to "leaky gut," by compiling facts accumulated from the era of focused infection theory to the age of revolution in microbiome research. which, because it has a poorer structural foundation than a desmosome, is more susceptible to microbial infiltration. Microbial biofilms in the GS can form and persist for a long time, in contrast to biofilms on the skin and intestinal mucosa, which naturally shed. Therefore, we stress that the GS and the JE are the weakest points for germs to enter the human body, making the leaky gum equally as significant as, if not more important than, the leaky gut.

Researchers' focus has recently been drawn to the link between oral cells and gum disorders, which pose a serious threat to people's overall health as a result of recent advancements in periodontal studies. Complementary Metal Oxide Semiconductors (CMOSs), one of many microfabrication technologies, allow for the creation of inexpensive integrated sensors and circuits for the quick and precise evaluation of living cells that can be used for the early detection and management of periodontal diseases. The CMOS capacitive sensing platform described in this study can be used as an alternative for the investigation of salivary cells, such as oral neutrophils. This platform is made up of two sensing electrodes that are linked to a read-out capacitive circuitry that was created and manufactured on the same chip utilising Austria Mikro Systeme (AMS) 0.35 m CMOS technology.