DOI: 10.37421/2472-1042.2024.9.214
Multidrug resistance proteins (MRPs) constitute a family of membrane-bound transporters that play a pivotal role in cellular detoxification and the disposition of endogenous and exogenous compounds. Their involvement in the efflux of various therapeutic agents has profound implications for pharmacokinetics, drug efficacy, and resistance development. This article aims to elucidate the intricate interplay between MRPs and their drug substrates, exploring the mechanisms underlying drug resistance and providing insights into potential therapeutic strategies.
DOI: 10.37421/2472-1042.2024.9.211
DOI: 10.37421/2472-1042.2024.9.212
DOI: 10.37421/2472-1042.2024.9.213
DOI: 10.37421/2472-1042.2024.9.215
DOI: 10.37421/2472-1042.2024.9.216
Methyl-containing pharmaceuticals play a pivotal role in modern medicine, contributing significantly to various therapeutic interventions. This class of compounds encompasses a diverse range of drugs, including methylphenidate for attention-deficit hyperactivity disorder (ADHD), methotrexate for cancer and autoimmune diseases and methylcobalamin for neurological disorders. Methyl groups confer unique pharmacological properties, influencing drug efficacy, metabolism and pharmacokinetics. Understanding the role of methyl-containing pharmaceuticals is crucial for optimizing therapeutic outcomes and advancing drug development in the healthcare landscape.
DOI: 10.37421/2472-1042.2024.9.217
Tuberculosis (TB) remains a global health challenge, necessitating continuous advancements in treatment strategies. This abstract delves into recent breakthroughs in TB drug development, including novel compounds targeting drug-resistant strains and innovative delivery mechanisms to enhance efficacy and patient compliance. By exploring the latest research and clinical trials, this abstract highlights the promising avenues for revolutionizing TB treatment and ultimately reducing the burden of this infectious disease worldwide.
DOI: 10.37421/2472-1042.2024.9.218
Impact analysis of drug action in healthcare is crucial for comprehending the effectiveness, safety and implications of pharmaceutical interventions. This analysis evaluates the multifaceted consequences of drug actions on patient outcomes, healthcare systems and society at large. It encompasses factors such as therapeutic efficacy, adverse effects, cost-effectiveness and patient adherence. By elucidating the significance of drug action, this study contributes to informed decision-making processes in healthcare, facilitating the optimization of treatment strategies and the advancement of patient care.
DOI: 10.37421/2472-1042.2024.9.219
Pharmacoeconomics education plays a pivotal role in optimizing healthcare value by equipping healthcare professionals with the necessary skills to assess the economic implications of pharmaceutical interventions. This paper explores the significance of pharmacoeconomics education in enhancing decision-making processes within healthcare systems, ultimately contributing to improved allocation of resources and better patient outcomes. Through comprehensive training in pharmacoeconomics, healthcare professionals can effectively evaluate the cost-effectiveness of treatments, consider budgetary constraints and prioritize interventions that offer the greatest value for money. By integrating pharmacoeconomics education into healthcare curricula, institutions can empower future practitioners to navigate complex economic considerations and drive sustainable advancements in healthcare delivery
DOI: 10.37421/2472-1042.2024.9.220
Pharmacoeconomics: Open Access received 106 citations as per Google Scholar report