France
Case Report
Guillain-Barre Syndrome Associated with Rapid Immune Reconstitution
Following a Tandem Autologous Hematopoietic Stem Cell Transplantation.
Study of a Case and Review of the Literature
Author(s): Guilloton L, Wey PF, Faulcon C, Ghesquières H, Petitjean F, Nicolas Virelizier E, A Drouet and Biron PGuilloton L, Wey PF, Faulcon C, Ghesquières H, Petitjean F, Nicolas Virelizier E, A Drouet and Biron P
Introduction: Guillain-Barré syndrome (GBS) is a frequent cause of neuromuscular paralysis and usually occurs after an immunoallergic reaction, most often after respiratory or gastrointestinal infection. However, rare cases of Guillain-Barré syndrome are described, associated with hematopoietic stem cell transplantation.
Observation: Patient n° 20452690. The authors report the case of 21 years old man, treated for Hodgkin lymphoma with a recurrence at 18 months, who enjoyed second autologous hematopoietic stem cell transplantation after conditioning chemotherapy, then developed a Guillain-Barré syndrome. Plasma exchanges were made before a neurological worsening. Thereafter, five cycles of intravenous immunoglobulin were performed monthly. Unfortunately this development was hampered by mechanical res.. Read More»
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