Indonesia
Research Article
Correlation of Estradiol and Estriol Serum Levels to Melasma Severity in Pregnant Women
Author(s): Aunur Rofiq, SHW Tantari, A Widiatmoko and Dyah Ayu SavitriAunur Rofiq, SHW Tantari, A Widiatmoko and Dyah Ayu Savitri
Combination of hormonal change, ultraviolet radiation and genetics are the most responsible factors in melasma. One of pigmentation change caused by pregnancy is melasma. The critical key to describe hyperpigmentation process is increased levels of estradiol and estriol. This study is aimed to determined correlation of serum levels of estradiol and estriol to melasma severity in pregnant women. This cross-sectional study was conducted with consecutive sampling in pregnant women with melasma. This study was conducted from June to July 2017 at Dr. Saiful Anwar Regional Hospital, Malang, East Java, Indonesia. Pregnant woman with melasma (15-49 years) was included and pregnant women with the history of melasma not caused by pregnancy, which used hormonal contraception or oral hormone therapy containing estrogen and took oral phototoxic drugs, were excluded. Anamnesis, physical examination.. Read More»
DOI:
10.4172/2376-0427.1000268
Journal of Dermatology and Dermatologic Diseases received 4 citations as per Google Scholar report