Tunisia
Case Report
Rituximab (RTX) and Plasmapheresis in a Recurrent Segmental and Focal
Glomerulosclerosis (FSGS) Case after Kidney Transplantation
Author(s): Abdellaoui I, Azzabi A, Sahtout W, Benaicha N, Guedri Y, Zallama D and Achour AAbdellaoui I, Azzabi A, Sahtout W, Benaicha N, Guedri Y, Zallama D and Achour A
A 21-year-old male patient whose primary kidney disease was focal segmental glomerulosclerosis (FSGS) received a living kidney transplant 7 years after starting hemodialysis (haploidentic from his mother). His kidney disease was primary recurrent FSGS treated since the age of four with corticosteroids and switching different options of Immunosuppressive treatment Calcineurin inhibitors and mycophenolate Mofetil). The transplantation induction protocol was Corticosteroid (CS) boli and Basiliximab without added preventive Therapeutic Plasma Exchange (TPE/ Plasmapheresis) sessions. Then for maintain, he took CS, Mycophenolate Mofetil and Cyclosporine A. After 9 liters of urine output at day zero after transplantation, he developed severe recurrence of proteinuria (up to 23 g/24 hat day 2) and anuria with creatinin level ascension to reach 500 micromol/l. The immunosuppressive treatment c.. Read More»
DOI:
10.37421/jnt.2019.9.333
Journal of Nephrology & Therapeutics received 784 citations as per Google Scholar report