France
Case Report
Celiac Disease Secondary to Tacrolimus after Human Renal Transplantation: A Case Report
Author(s): Narjes Ben Aicha, Sahtout Wissal, Azzabi Awatef, M'rabet Sanda, Toumi Salma, Guedri Yosra, Zallema Dorsaf and Achour AbdellatifNarjes Ben Aicha, Sahtout Wissal, Azzabi Awatef, M'rabet Sanda, Toumi Salma, Guedri Yosra, Zallema Dorsaf and Achour Abdellatif
Celiac disease is an autoimmune disorder affecting primarily the small intestine. Although rare celiac disease is a possible cause of diarrhea after renal transplantation. Our case is the first to report that tacrolimus could be cause of celiac disease after renal transplantation. A woman aged 34 years old, with a renal transplantation from a cadaveric donor. For maintenance therapy, she underwent tri-therapy with Tacrolimus. She was complaining from chronic diarrhea with weight loss unimproved at 16 months after the TR and despite the switch from Mycophenolate mofetil to Azathioprine. She had an anemia and signs of malabsorption with a congestive duodenitis in the gastroscopy and villous atrophy in moderate area in the biopsy. Celiac serology was positive. The patient underwent gluten-free diet during 6 months without improvement. Tacrolimus was stopped and switched to Cyclosporine A.. Read More»
DOI:
10.4172/2161-0959.1000277
Journal of Nephrology & Therapeutics received 784 citations as per Google Scholar report