Veterinary Science & Technology

Addisu Demeke

Publications

• Review Article
  Current Advancements on the Significance of Oncolytic Viruses in the Treatment of Tumor Cells
  Author(s): Addisu Demeke, Asmelash Tassew and Aklilu FelekeAddisu Demeke, Asmelash Tassew and Aklilu Feleke
  
  The occurrence and severity of tumor, which is caused by many factors and etiological agents, become rapid and its distribution is worldwide that lead to death of many individuals. In order to avoid associated complications scientists discovered a means for the removal of tumor using oncolytic virus called virotherapy. This review is aiming to give highlight about the current advancements on the significance of oncolytic viruses in the treatment of tumor cells. Oncolytic viruses carry the promise to efficiently target cancer cells for destruction and spread throughout tumor tissue to reach distant loci without causing collateral damage to healthy tissues. Current oncolytic virotherapy strategies are based on the common molecular mechanisms of viral infection and cell transformation, like apoptotic dysregulation and cell cycle disruption. In this regards this time scientists is being d.. Read More»
  DOI: 10.4172/2157-7579.1000308

  Abstract PDF