Nigeria
Research Article
There is No Cryptococcal Antigenaemia among A Cohort of Children with Advanced HIV Infection in an Antiretroviral Therapy Programme in Makurdi, Nigeria
Author(s): Emmanuel Adémólá Anígilájé, Ayodotun Olutola, Othniel Dabit, Adekunle Olatayo Adeoti, Agnes Jane Emebolu and Jonah AbahEmmanuel Adémólá Anígilájé, Ayodotun Olutola, Othniel Dabit, Adekunle Olatayo Adeoti, Agnes Jane Emebolu and Jonah Abah
Introduction: Cryptococcal disease is an important opportunistic infection and a major contributor to mortality in HIV/AIDS. Unfortunately, there has been no data describing the burden of cryptococcosis in Nigerian HIV-infected children.
Methods: A cross-sectional study between January 2013 to September 2013 at the Federal Medical Centre, Makurdi to determine the prevalence and risk factors of cryptococcal antigenaemia among a cohort of consecutive HIV-infected children (≤15 years of age) with a CD4 count of ≤200 cells/mm3, including treatment-naive and those on Antiretroviral Therapy (ART). The cryptococcal antigen Lateral Flow Assay method was used twice on each sample collected from the children.
Results: A total of 699 children were seen but only 88 children had CD4 count of ≤200 cell/mm3. These 88 subjects included 47 Males and 41 Females (M: F, 1:0.9). T.. Read More»
DOI:
10.4172/2155-6113.1000261
Journal of AIDS & Clinical Research received 5061 citations as per Google Scholar report