Saudi Arabia
Research Article
The Prognostic Role of Pretreatment 18F-FDG (PET/CT) Maximum Standardized Uptake Value in Multiple or Oligometastatic Breast Cancer Patients
Author(s): Hala A El-Lathy, Ahlam A Dohal, Yasser Alassiri, Yasser Al Malki and Ehab IbrahimHala A El-Lathy, Ahlam A Dohal, Yasser Alassiri, Yasser Al Malki and Ehab Ibrahim
Purpose: To determine the prognostic role of pretreatment F-18FDG PET/CT maximum standardized uptake value (SUVmax) in metastatic breast cancer (MBC) patients and its correlation with clinicopathological parameters.
Materials and Methods: The pretreatment 18FDG-PET-CT SUVmax in MBC patients was compared with clinicopathological parameters. The prognostic value of pretreatment SUVmax for progression free survival (PFS) and overall survival (OS) were assessed using log rank test and cox regression analysis.
Results: Overall, 100 patients (77%) had evidence of visceral metastases while 30 patients (23%) had oligometastatic disease confined to bones only. The receiver operator curve (ROC) demonstrated that SUVmax of 4.4 and 7.7 to be the cutoff value for predicting PFS in patients with oligometastasis to bones and mult.. Read More»
DOI:
10.4172/2155-9619.1000236
Nuclear Medicine & Radiation Therapy received 706 citations as per Google Scholar report