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Journal of Computer Science & Systems Biology

ISSN: 0974-7230

Open Access

Ahmed Ahmed


France

Publications
  • Research Article
    Circular Code Signal in Frameshift Genes
    Author(s): Christian J. Michel and Ahmed AhmedChristian J. Michel and Ahmed Ahmed

    A trinucleotide circular code is a set of trinucleotides allowing the reading frame in genes to be retrieved locally, i.e. anywhere in genes and in particular without start codon, and automatically with a window of a few nucleotides. In 1996, a common circular code X has been identified simultaneously in two large populations of eukaryotic and prokaryotic genes. The method proposed here identifies periodic signals of this code X in the two frameshift types (+1 and -1) of both eukaryotic and prokaryotic frameshift genes. As expected by the code theory, the circular code modulo 3 signals move in the same direction of translational frameshifting. Finally, in 68% of frameshift genes in the RECODE 2 database, the frameshift type (+1 and -1) is automatically identified using only this circular code periodic signal. This circular code information constitutes a ne.. Read More»
    DOI: 10.4172/jcsb.1000069

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