School of Medicine, University of California at Riverside UCR ,
Riverside, California
Tanzania
Case Report
Understanding Minoxidil-Induced Pericardial Effusion
Author(s): Ahmed M ShafterAhmed M Shafter
Minoxidil is a powerful antihypertensive medication that has been used extensively to control blood pressure in patients with renal failure. Its mechanism of action is through a cyclic AMP-mediated effect on arteriolar smooth muscle, with little effect on veins causing a direct vasodilatation of peripheral blood vessels. Minoxidil use has been associated with cause and/or exacerbation of pericardial effusions both in dialysis patients and those with normal kidney function. We report a 58-year-old African American female with history of severe resistant hypertension that has been controlled by Minoxidil 5 mg po BID, and stage 3 chronic kidney disease who presented with shortness of breath, and headache. Blood pressure 240/124 mmHg. Her CT Brain revealed no intracranial bleed. Electrocardiogram showed normal sinus rhythm, with no ST/T wave changes. Cardiac biomarkers were normal. Howeve.. Read More»
DOI:
10.4172/2329-9517.1000323
Cardiovascular Diseases & Diagnosis received 427 citations as per Google Scholar report
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