Journal of Forensic Research

Akifa M

Publications

• Review Article
  Implications of Targeted Next Generation Sequencing in Forensic Science
  Author(s): Sobiah R, Syeda RH, Zunaira E, Nageen Z, Maria K, Syeda AZ, Shahana SM, Akifa M, Abdul J and Muhammad RKSobiah R, Syeda RH, Zunaira E, Nageen Z, Maria K, Syeda AZ, Shahana SM, Akifa M, Abdul J and Muhammad RK
  
  The outburst of next generation sequencing has outpaced the traditional capillary electrophoresis (CE) based forensic genomics in terms of throughput, scalability and allelic resolutions. The limitations of CE-based detection system for STRs (Short Tandem Repeats) and SNPs (Single Nucleotide Polymorphisms) markers associated with forensic DNA phenotyping have been greatly overcome through next generation sequencing (NGS). It offers simultaneous analysis of forensically relevant genetic markers including STRs, SNPs, mutations and transcripts to improve efficiency, capacity and resolution through massively parallel sequencing. The detailed sequence information in comparison with ever growing DNA databases across the world may aid mixture interpretation, and will ensure enhancement in statistical weight of the evidence. Nowadays, a total of 33 NGS machines with low to high thro.. Read More»
  DOI: 10.4172/2157-7145.1000416

  Abstract PDF