College of Veterinary Medicine,
Baghdad
Iraq
Research Article
Exploration of Steroidoginic Activity of Ketorolac on Isolated Leydig Cells of Goat (Capra hircus) In Vitro: Part II
Author(s): Al-Bayati MA and AI-Luhapy ZZAAl-Bayati MA and AI-Luhapy ZZA
In the present thesis was conducted to clarify the effect of ketorolac (NSAID) on the Leydig cells of goats to achieve the ketorolac event, by the evaluation steroidoginic activity of ketorolac series on Leydig cell concentrations in vitro. Mitochondrial defects reduction of functional processes of sterodoginc activity reduction of testosterone levels via mitotracker probe indicator, ketorolac may be affected on the steroidogenic acute regulatory (STAR) protein and translocator protein (TSPO). Ketorolac might mutilation and impair the cells were via the uncoupling of oxidative phosphorylation in the cells followed by uncouple mitochondrial respiratory chain as well as ATP depletion. Testosterone level displays in all treated maneuvers LH, LH-GnRH and GnRH in ketorolac challenge decrease testosterone levels at a concentration of ketorolac from 0.6-0.15 mM with the exception in.. Read More»
DOI:
10.4172/2157-7579.1000404
Veterinary Science & Technology received 4472 citations as per Google Scholar report