Journal of Clinical Case Reports

Alexandru Ulici

Publications

• Case Report
  Severe Kyphosis Secondary to Glucocorticoid-Induced Osteoporosis in Adolescent Twins with Congenital Adrenal Hyperplasia - A Case Report and Literature Review
  Author(s): Mădalina Carp, Iulia Tevanov, Catalin Florea, Alin Ladaru, Gabriel Sterian, Andrei Dusca and Alexandru UliciMădalina Carp, Iulia Tevanov, Catalin Florea, Alin Ladaru, Gabriel Sterian, Andrei Dusca and Alexandru Ulici
  
  Patients with Congenital Adrenal Hyperplasia (CAH) need a life-long treatment with glucocorticoids (GC) which affects bone quality and bone density. We report the clinical cases of twin sisters diagnosed at birth with CAH (simple virilization form). They both received treatment with GC and were diagnosed with severe Hyperkyphosis; they underwent transpedicular vertebral instrumentation, Ponte osteotomies and posterior autograft spinal fusion. Post-surgery evolution was favourable. After 3 years, one of the patients suffered a spinal implant infection that needed debridement and drainage. Patients with long term treatment with GC have a higher risk for osteoporosis than the general population. While monitoring the patients we should take into consideration the bone`s status and preventive measures against osteoporosis. It is important to diagnose the deformities of the spine at a young.. Read More»
  DOI: 10.4172/2165-7920.1000977

  Abstract PDF