Journal of AIDS & Clinical Research

Alfonso Cabello

Publications

• Research Article
  Long-Term Efficacy of Nevirapine Plus Co-Formulated Abacavir/Lamividune as Simplification Therapy in HIV-Infected Patients with Undetectable Viral Load
  Author(s): Alfonso Cabello, José Casas, Juan Alfredo López, Rosa García Delgado, Manuel L. Fernández Guerrero and Miguel GórgolasAlfonso Cabello, José Casas, Juan Alfredo López, Rosa García Delgado, Manuel L. Fernández Guerrero and Miguel Górgolas
  
  Background: The long-term efficacy of NVP+ABC+3TC as a simplification strategy for the treatment of HIV-1 infected patients with undetectable viral load has not been properly assessed in randomized trials. This low-cost treatment with limited renal and bone side effects must be of particular interest in this era of cost-containment urgency and also in limited resource settings. Methods: Observational study of 232 HIV1-infected patients with undetectable viral load who initiated nevirapine (NVP) + abacavir (ABC) + lamivudine (3TC). Reasons for the switching were treatment simplification (56%), renal problems (6%), osteopenia/osteoporosis (7%), hyperlipidemia (11%) and others (20%). HIV-1 viral load, CD4 cell count and fasting biochemistry profiles were determined on a routine clinical practice. The aim of the study was to evaluate long-term efficacy of this c.. Read More»
  DOI: 10.4172/2155-6113.1000457

  Abstract PDF