Journal of Bioanalysis & Biomedicine

Alok Bandyopadhyay

Publications

• Review Article
  Transdermal Drug Delivery System-Quality by Design Approach
  Author(s): Alok BandyopadhyayAlok Bandyopadhyay
  
  Transdermal Drug Delivery System (TDDS) is a delivery system of continuous drug penetration through the skin at a reproducible rate over the intended application time period. This process is accomplished by two technologies: (a) Passive, and (b) Active. The former uses particulate system or chemical penetration system enhancers, whereas active technology uses electrical device to overcome skin barriers. Some of the major reported products have quality issues. Several guidance’s are published on this aspect. For better understanding, FDA suggested to perform the development of delivery system through Quality by Design (QbD) approach. Although there are some limitations e.g. skin tolerability, skin barrier properties and variability of application site conditions, but also there are several advantages. Convenience, visibility of drug administration, consistent serum leve.. Read More»
  DOI: 10.4172/1948-593X.1000181

  Abstract PDF