King Abdulla Medical City, 3790 wali alahad street, Makkah
Saudi Arabia
Case Report
Hoffmann’s Syndrome a Presenting Manifestation of Hypothyroidism
Author(s): Amal AlkhotaniAmal Alkhotani
Hypothyrodisim associated with different neuromuscular manifestations. Rarely patient with hypothyroidism may develop muscular pseudohypertrophy a condition called Hoffmann’s syndrome in adults. We report a patient present mainly with myelgia, cramps, calf pseudohypertrophy and persistently elevated Creatine Kinase (CK) with absence of other systemic symptoms of hypothyroidism. His laboratory works revealed severe hypothyroidism. Treatment with L-thyroxine resulted into disappearance of symptoms, normalization of CK and return of calf size to normal. Hypothyrodism should be considered when evaluating patients with neuromuscular complaints even in absence of systemic symptoms.
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DOI:
10.4172/2165-7920.1000279
Journal of Clinical Case Reports received 1345 citations as per Google Scholar report