NUB
Egypt
Research Article
Determination of Clopidogrel Bisulphate in Plavix Tablet and Human Biological Fluids Utilizing Chemically Modified Carbon Paste Sensor
Author(s): Amal Fouad KhorshidAmal Fouad Khorshid
The fabrication and the performance response characteristics of a novel sensitive, selective, simple, and rapid sensor for the determination of Clopidogrel bisulphate (CLO-H2SO4) were described. The sensing modified carbon paste sensor comprised of an ion-pair based on Clopidogrel with silico tungastate (CLO-ST) where this study included: composition, usable pH range, response time and temperature. The sensorex hibiteda wide linear dynamic concentration ranging from 1.00x10−7-1.00x10−2 and the usable pH ranges from 1.2-4.8 with the response time ranging from (5-8 sec) which is much faster compared to liquid ISEs with a detection limit equals 0.34 nM. The selectivity of the sensor (CLOH2SO4) was applied with respect to a many of organic and inorganic cations, amino acids and sugars. The application of the sensor (CLO-H2.. Read More»
DOI:
10.4172/2155-9821.1000154
Journal of Bioprocessing & Biotechniques received 3351 citations as per Google Scholar report