Kenya
Research Article
Impact of First Line Antiretroviral Therapy on Clinical Outcomes Among
HIV-1 Infected Adults Attending One of the Largest HIV Care and
Treatment Program in Nairobi Kenya
Author(s): Musa Otieno Ngayo, Faith Apolot Okalebo, Wallace Dimbuson Bulimo, Christina Mwachari, Anastasia Nkatha Guantai and Margaret OlukaMusa Otieno Ngayo, Faith Apolot Okalebo, Wallace Dimbuson Bulimo, Christina Mwachari, Anastasia Nkatha Guantai and Margaret Oluka
Objective: This study evaluated the immunologic (CD4 cell count), virological (HIV RNA viral load), hepatic (alanine and aspartate aminotransferase - ALT and AST), renal (creatinine) and hematological (hemoglobin -HB, White Blood Cell - WBC, Lymphocytes - LYM and platelets - PLT) response to a six months ART treatment among HIV participants in Nairobi Kenya.
Methods: Blood samples were obtained from 599 consenting HIV infected participants receiving HIV treatment in Nairobi. CD4 cell counts were measured using flow cytometer and viral load determined using real-time polymerase chain reaction. The blood hematology, liver and kidney function tests were also measured. One-way ANOVA and Linear regression analysis were conducted.
Results: The median age at ART initiation was 41 years (IQR 35-47 years). .. Read More»
DOI:
10.4172/2155-6113.1000615
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report