Medicinal Chemistry

Andreas Holzinger

Publications

• Research Article
  Discovery of Characteristics of Patients with Increased Level of Inflammation
  Author(s): Ljiljana Trtica Majnaric, Pinar Yildirim and Andreas HolzingerLjiljana Trtica Majnaric, Pinar Yildirim and Andreas Holzinger
  
  This paper is a study on knowledge discovery for the prediction of characteristics of older patients with increased level of inflammation. The etiology of inflammation is thought to be multifactorial and associated with the development of chronic aging diseases. Chronic low grade inflammation, expressed by slightly elevated serumconcentrations of the inflammatory marker C-reactive protein (CRP), has been showed to be associated with increased frailty and overall and specific cardiovascular and noncardiovascular mortality. However, it has not been discovered before which conditions, taken all at once, are associated with elevated systems level of inflammation. To answer this question, we used the group of older primary health care attenders, burdened with multiple chronic conditions and described their health status by many aspects. The dataset was com.. Read More»
  DOI: 10.4172/2161-0444.1000310

  Abstract PDF