Division of Oncology, Weill Cornell Medical Center,
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Case Report
Effects of Caffeine on Salivation
Author(s): Andrei Barasch and Sara C GordonAndrei Barasch and Sara C Gordon
Background: Caffeine is a methylxanthine which may decrease salivation through adrenergic mechanisms. Few studies have formally tested whether caffeine actually decreases saliva production.
Methods:Eleven volunteers collected unstimulated 1-minute saliva production (1-MSP) after an overnight fast, followed shortly by a stimulated 1-MSP while chewing a stick of chewing gum. We then asked them to drink a beverage randomly selected to contain either regular or decaffeinated instant coffee. Caffeine content was doubleblinded. 1-MSP, both unstimulated and stimulated were then collected 30, 60, 90, and 120 minutes later. The following morning the subject followed the same protocol but drank the other kind of beverage. We used a mixedeffects linear model to analyze our data.
Results: The adjusted mean difference between d.. Read More»
DOI:
10.4172/2471-8726.1000107
Oral Health Case Reports received 120 citations as per Google Scholar report