Journal of Bioengineering & Biomedical Science

Andreyevich KL

Publications

• Research Article
  On Optimal Control Model for the Treatment of Dual HIV-Parasitoid Pathogen Infection
  Author(s): Bassey E, Anande RK and Andreyevich KLBassey E, Anande RK and Andreyevich KL
  
  Following the insurmountable and seeming incurable status for the most acclaimed infectious disease – HIV, and which have been worsened by its allies of infectious diseases, this paper projected using ordinary differential equations, a 4-Dimensional mathematical model that accounted for the percentage optimal benefits and the methodological application of chemotherapy - RTI, in the interaction of dual HIV- parasitoid pathogen infectivity with the human immune system. Simple analytical optimal control method was deployed, primed by the maximization of healthy immune system on the basis of control effect of chemotherapy on viruses’ infectivity. Using Pontryagin’s Maximum Principle, the study established the model dynamical optimal control as a composition of system state variables, coupled with four adjoint systems with corresponding initial and transversality conditio.. Read More»
  DOI: 10.4172/2155-9538.1000212

  Abstract PDF