Journal of Computer Science & Systems Biology

Anna L Proskura

Publications

• Research Article
  The Protein-Protein Interaction Networks of Dendritic Spines in the Early Phase of Long-Term Potentiation
  Author(s): Anna L Proskura, Aleksander S Ratushnyak and Tatyana A ZaparaAnna L Proskura, Aleksander S Ratushnyak and Tatyana A Zapara
  
  The neuron is a basic element of brain networks. Changes of nerve cell excitability, the conduction of excitation, synaptic memory-forming in the case of the temporal coincidence of synaptic events are the obvious functions of the neuron - element of brain networks. The implementation of the neuron function depends on actions of its numerous molecular systems. The generalization of the complex processes of emergence of synaptic memory, that occur even in separate neuronal compartments, without special tools is a difficult, if at all possible, task. A technology that combines the creation of databases (elements and their relationships) with a visual representation in the form of networks facilitates this process. The developed protein-protein interaction network in dendritic spines of hippocampal pyramidal neurons facilitates the synthesis of numerous exper.. Read More»
  

  Abstract PDF