Journal of Bioprocessing & Biotechniques

Antonella Tinelli

Publications

• Research Article
  Multilineage Differentiation Potential of CNS Cell Progenitors in a Recent Developed Gilthead Seabream (Sparus aurata L.) Nervous Model
  Author(s): Maria Pia Santacroce, Antonella Tinelli, Anna Selene Pastore, Michele Colamonaco and Giuseppe CrescenzoMaria Pia Santacroce, Antonella Tinelli, Anna Selene Pastore, Michele Colamonaco and Giuseppe Crescenzo
  
  Neural Progenitor Cells (NPCs) have gathered more and more attention in the field of Neural Stem Cells (NSCs). However, the multilineage differentiating behavior of these cells and their contribution to tissue regeneration, almost in lower vertebrate taxa, remain unknown. Since the early 1970s, many comparative studies have been performed using immunocytochemical screening on the brains of several vertebrate taxa, including teleosts, in order to identify these cells, even if the data are sometimes contrasting. This study aims: (1) to investigate in vitro the potential proliferative role of NPCs and Radial Glia Progenitors (RGP) in seabream neurogenesis; (2) to reveal the strict ability of fish NSCs to undertake the multilineage development and differentiation in neurons, astrocytes and oligodendrocytes. By the use of double Immunofluorescence (IF) analysis and phase contrast microscop.. Read More»
  DOI: 10.4172/2155-9821.1000186

  Abstract PDF