India
Research Article
Ionizing Radiation Increases the Circulatory Endothelial Progenitor Cell Population in Glottic Cancer Patients
Author(s): Sayantan Bhattacharyya, Tapas Maji, Dilip Kumar Ray, Anup Kumar Bhowmick and Nabendu MurmuSayantan Bhattacharyya, Tapas Maji, Dilip Kumar Ray, Anup Kumar Bhowmick and Nabendu Murmu
Background: Cancer of the throat or larynx is one of the predominant cancer types in India and Intensity Mediated Radiation Therapy (IMRT) is the most crucial treatment regimen against the disease. We aimed to examine the effect of Circulating Endothelial Progenitor (CEP) cells in Laryngeal cancer patients undergoing radiation therapy.
Patients: Five Laryngeal cancer patients were selected for the work. All patients were suffering from Squamous Cell Carcinoma (SCC) of the glottis and admitted to the institute with CT1 and CT2 stage of tumor with no lymph node metastasis (CN0). After thorough check up the patients were subjected to conventional mononodal radiotherapy (IMRT), fractionated doses to the highest dose (1.8-2 Gy per fraction). Peripheral Blood Mononuclear Cells (PBMC) was isolated from all 5 patients and flow cytometric analysis (using anti CD 44 and CD309 monoclonal.. Read More»
DOI:
10.4172/2155-9619.1000251
Nuclear Medicine & Radiation Therapy received 706 citations as per Google Scholar report