Immunochemistry & Immunopathology

Aref MI

Publications

• Research Article
  Immunomodulatory Role of Treg Lymphocytes in Chronic Hepatitis C Patients
  Author(s): Aref MI, Ibrahim IA, Ahmed SS and El-Azim Mansour MAAref MI, Ibrahim IA, Ahmed SS and El-Azim Mansour MA
  
  Background: Regulatory T cells (Tregs) have a fundamental job in keeping up a harmony between forestalling immunopathology and enabling the insusceptible reaction to clear infections, in HCV infection, elevation of Tregs may cause insistent HCV infection. Objective: The current work aimed to clarify the immunomodulatory role of CD4+ CD25+ Foxp3+ Tregs in chronic hepatitis C (CHC) patients. Subjects and methods: This study incorporated two groups: 50 patients with chronic HCV infection of different classes of Child-Pugh classification (Child A, B and C) and control group; 25 healthy subjects. All patients were exposed to full history taking and finish clinical examination, as well as routine lab analysis including CBC, AST, ALT, ALP, GGT, PT, INR, blood urea, serum creatinine, ANA. HCV-Abs was me.. Read More»
  

  Abstract PDF