Journal of AIDS & Clinical Research

Ariel Goldenthal

Publications

• Research Article
  Frequent Episodes of Detectable Viremia in HIV Treatment-Experienced Children is Associated with a Decline in CD4+ T-cells Over Time
  Author(s): Elijah Paintsil, Ryan Martin, Ariel Goldenthal, Shreya Bhandari, Warren Andiman and Musie GhebremichaelElijah Paintsil, Ryan Martin, Ariel Goldenthal, Shreya Bhandari, Warren Andiman and Musie Ghebremichael
  
  Background: The clinical consequences of the magnitude and the duration of detectable viremia in HIV-infected children have not been well characterized. We examined the predictors and immunologic consequences over time of frequent episodes of detectable viremia in HIV-infected children followed at Yale-New Haven Hospital. Methods: We analyzed the CD4+ T-cell and HIV viral load over a 19-year period (1996 to 2013) of 104 HIVinfected children enrolled in the Yale Prospective Longitudinal Pediatric HIV Cohort. Both CD4+ T-lymphocytes and HIV viral load were measured at clinic visits every 3 to 4 months. Longitudinal data analyses using polynomial random coefficients models were conducted to examine overtime changes in CD4+ T-cell counts by frequency of episodes of detectable viremia. Moreover, regression analyses using logistic regression model.. Read More»
  DOI: 10.4172/2155-6113.1000565

  Abstract PDF