United Kingdom
Case Report
Small Cell Carcinoma of the Upper Urinary Tract: A Case Report and
Review of Existing Cases
Author(s): Aristeidis Alevizopoulos, Huay Shan Yuen, Soumadri Sen and Rowan CaseyAristeidis Alevizopoulos, Huay Shan Yuen, Soumadri Sen and Rowan Casey
Primary extra-pulmonary small cell carcinomas (SCC) are rare, with <40 cases reported in the current literature. Only 1% of all primary upper urinary tract tumors are SCCs. We present a new case of a primary SCC of the right upper urinary tract. A 78-year-old male patient presented with frank hematuria and a lump in the left posterior triangle of his neck. CT imaging revealed a right renal pelvic mass associated with suspected liver metastases, cervical and retroperitoneal lymphadenopathy. Rigid ureteroscopy demonstrated a tumor involving the right ureter. Immunohistochemical analysis of neck and ureteric biopsies revealed high proliferative activity and positive CD56 and TTF1 markers, in keeping with a diagnosis of small cell carcinoma. The patient was offered systemic chemotherapy, which he declined. He developed further skeletal metastases and underwent treatment with radiothera.. Read More»
DOI:
10.4172/2165-7920.1000811
Journal of Clinical Case Reports received 1345 citations as per Google Scholar report