Saudi Arabia
Research Article
Factors Influencing the Outcome of Hematopoietic Stem Cell Transplantation in Pediatric Acute Myeloid Leukemia: Single Institution Results from Saudi Arabia
Author(s): Al-Sweedan S, Siddiqui K, Jafri R, Al-Ahmari A, Ayas M and Al-Seraihy AAl-Sweedan S, Siddiqui K, Jafri R, Al-Ahmari A, Ayas M and Al-Seraihy A
Medical records of 73 patients with AML who underwent HCT, 2005-2011. The OS was 51.8% and the EFS were 48%. Median follow-up time for the cohort was 50.667 ± 2.4 months (95%CI: 45.9-55.4). 39 patients were alive with a median follow-up time of 50.1 months (Min: 1.8, Max: 111.8). Sixteen patients survived for more than 5 years (Min: 65.2, Max: 111.8 months). The cumulative incidence of acute GVHD was 6.8 ± 2.9 and of chronic GVHD was 9.9 ± 3.6. Median time to ANC and platelet recovery was 16 days (range 9-37) and 29 days (range 15-180) respectively. Three patients acquired CMV infection after transplant. There was a significant impact of patient’s age at diagnosis on the overall survival (Infantile: 100%, others: 45.6% ± 6.4%, P=0.016) and event free survival (Infantile: 100%, others: 40.6% ± 7.1%, P=0.013). Percentage of blasts at transplant, patients o.. Read More»
DOI:
10.4172/2165-7831.1000163
Journal of Blood & Lymph received 443 citations as per Google Scholar report