Cancer Science & Therapy

Ayman Maher Abdel Moneem Ibrahim

Publications

• Research Article
  Investigation of Telomerase Activity in Inflammatory and Non Inflammatory Breast Cancer
  Author(s): Ayman Maher Abdel Moneem Ibrahim, Salwa Farouk Sabet and Mohamed El-ShinawiAyman Maher Abdel Moneem Ibrahim, Salwa Farouk Sabet and Mohamed El-Shinawi
  
  Background: Inflammatory breast cancer (IBC) is an aggressive type of breast cancer disease that has a high incidence in Egypt than western countries. It is characterized by rapid progression, involvement of dermal lymphatic emboli and extensive lymph node involvement. Basic and translational studies are needed to define IBC disease biology and identify specific biomarkers have been limited by the paucity of patient samples. Hence, the current study aimed to introduce the telomerase activity level as a novel diagnostic marker for breast cancer and specifically for IBC to be differentiated from non-IBC.   Methods: Breast cancer patients were enrolled from Ain Shams University hospitals in Cairo, divided into two groups: IBC (n=26) and non-IBC (n=27). Tissue samples were collected during modified radical mastectomy. TRAP (Telomerase r.. Read More»
  DOI: 10.4172/1948-5956.1000168

  Abstract PDF