West Indies
Research Article
Associations Between Antibodies Against the Endothelial Cell and T.gondii; Cytomegalovirus in Serum of Children with Cochlear Implant Surgery
Author(s): Samileh Noorbakhsh, Mohammad Farhadi, Ahamad Daneshi, Azardokht Tabatabaei, Emam H jomeh and Yaser GhavamiSamileh Noorbakhsh, Mohammad Farhadi, Ahamad Daneshi, Azardokht Tabatabaei, Emam H jomeh and Yaser Ghavami
Background: Cytomegalovirus (CMV) and T. gondii are two common causes of SNHL (Sensorineural hearing loss) in Iranian children. Immune-mediated vascular damage induced by endothelial cell antibodies may have a prominent role in sensorineural hearing loss. Objectives: To determine the serum CMV and T. gondii antibodies against endothelial cell in children with profound SNHL and cochlear implant surgery.
Materials & Methods: A cross sectional study was performed on 76 cases with severe SNHL (mean age 32 ± 30.6 months) at cochlear implant ward of Rasoul hospital, Tehran Iran (2008-2010). The titers of antibodies against endothelial cell (Indirect immunofluorescence assay); were determined in sera of 66 cases. Specific antibodies (IgG & IgM) against T. gondi, CMV (Enzyme linked immunosorbent assay) determined in Idiopathic SNHL cases.
Results: Idiopathic typ.. Read More»
DOI:
10.4172/2155-6113.1000197
Journal of AIDS & Clinical Research received 5061 citations as per Google Scholar report