Journal of Forensic Research

Azumi Kuse

Publications

• Research Article
  Immunohistochemical Characterization of Sudden Death While Bathing:Evaluating the Expression of SP-A, HSP70 and c-Fos Following Drowning and Thermal Stress
  Author(s): Makoto Sakurada, Migiwa Asano, Azumi Kuse, Mai Morichika, Kanako Nakagawa and Yasuhiro UenoMakoto Sakurada, Migiwa Asano, Azumi Kuse, Mai Morichika, Kanako Nakagawa and Yasuhiro Ueno
  
  Sudden death while bathing is a major issue in elderly Japanese individuals. Despite its growing incidence, the exact processes underlying sudden death while bathing remain unknown. This study was designed to establish reliable diagnostic markers for drowning while bathing, as well as to assess the pathological conditions associated with sudden death while bathing, by analyzing the immunohistochemical intensity and localization of surfactant protein-A (SP-A), heat shock protein 70 (HSP70) and c-Fos protein in the lungs and central nervous system, including the cerebral cortex and hippocampus. We found that a distinct pattern of immunohistochemical expression of SP-A, HSP70 and c-Fos in the lung can be utilized to diagnose drowning. In most of these individuals, c-Fos protein was absent from the central nervous system, providing insight into patterns of .. Read More»
  DOI: 10.4172/2157-7145.1000249

  Abstract PDF