South Africa
Research Article
Vulval Involvement in Acquired Immunodeficiency Syndrome-Associated
Disseminated Histoplasmosis
Author(s): Ramdial PK, Sing Y, Ramburan A, Nargan K, Singh B, Bagratee JS and Calonje ERamdial PK, Sing Y, Ramburan A, Nargan K, Singh B, Bagratee JS and Calonje E
Background: Female genital tract, including vulval, histoplasmosis is reported rarely despite an increased propensity for cutaneous involvement by disseminated histoplasmosis (DH), even in patients with acquired immunodeficiency syndrome (AIDS). Methods: Sixteen year retrospective study investigating vulval involvement by histoplasmosis. Results: Of 239 patients with DH, 6 had vulval involvement and were confirmed to have HIV infection and AIDS. Seventeen biopsies (9 vulval, 8 extravulval) from these 6 patients form the study cohort. Patients 1 to 4 had simultaneous vulval (5) and extravulval (5) cutaneous biopsies. Eight cutaneous biopsies demonstrated diffuse dermal infiltration by histiocytes containing budding yeasts of H. capsulatum variant capsulatum (HCVC). A single thigh lesion demonstrated diffuse dermal karyorrhexis and myriad extracellular HCVC and a lymph node were diffu.. Read More»
DOI:
10.4172/2155-6113.1000632
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report