Indiana
Research Article
The Interleukin 8 Expression and its Possible Relationship with Degenerated and Injured Human Intervertebral Discs
Author(s): Basit Saleem Qazi, Tang Kai and Asma Saleem QaziBasit Saleem Qazi, Tang Kai and Asma Saleem Qazi
Purpose: Cervicaland Lumbar degenerative disc diseases (DDD) are a common disease of advanced age characterized by progressive changes in the intervertebral disc and associated structures. There have been great efforts for years to explain its pathophysiological mechanism(s). This study aims to provide the expression of IL-8 in a population of patients with lumbar disc herniation, cervical stenosis and vertebral fracture.
Material and methods: We compared the level of IL-8 expression in the non-degenerated and degenerated intervertebral disc samples obtained from patients who underwent surgery for vertebral fracture (non degenerated disc), lumbar disc herniation and cervical stenosis (degenerated disc), whose clinical and radiological features were suggestive of disc degeneration. IL-8 expression was studied by using the western blot, immuno.. Read More»
DOI:
10.4172/2165-7939.1000135
Journal of Spine received 2022 citations as per Google Scholar report