Nigeria
Review Article
Transfusion Therapy in Sickle Cell Disease
Author(s): Kingsley Akaba, Bassey O Bassey, Idongesit Akpan and Ofonimeh E EffiongKingsley Akaba, Bassey O Bassey, Idongesit Akpan and Ofonimeh E Effiong
Background: Blood transfusion is an important therapy in the management of sickle cell disease (SCD); especially in developing countries. Transfusion aids the restoration of the oxygen carrying capacity in patients with SCD and also prevents vaso-occlusion by dilution of the Hbs in circulation. However, there is paucity of information on transfusion as a therapy in the management of SCD.
Aim and objective: This study is aimed at reviewing the available publications on transfusion as a therapy for SCD management.
Materials and methods: Relevant literatures were searched on databases including PubMed, Google Scholar, Scopus, Cochrane and standard texts on haematology and transfusion medicine. The keywords used in the search are sickle cell disease, transfusion, simple and chronic transfusion, complications of transfu.. Read More»
DOI:
10.37421/jbl.2019.9.244
Journal of Blood & Lymph received 443 citations as per Google Scholar report