International Journal of Neurorehabilitation

Bhuban Ruidas

Publications

• Review Article
  Role of Curcumin in Treatment of Alzheimer Disease
  Author(s): Chitrangada Das Mukhopadhyay, Bhuban Ruidas and Sutapa Som ChaudhuryChitrangada Das Mukhopadhyay, Bhuban Ruidas and Sutapa Som Chaudhury
  
  A lot of research findings support that curcumin (diferuloyl methane) has antioxidant, anti-inflammatory and antitumor activity. In India, curcumin has a widespread use as food additive and herbal medicine for human diseases without any side effect. Though curcumin is well established as an anticancer agent but there are a few reports about its promising role against amyloid diseases. According to recent finding curcumin play a crucial inhibitory role in pathophysiology of Alzheimer’s disease (AD). Oral administration of curcumin or its metabolites has shown the inhibition of Aβ deposition, Aβ oligomerization and tau phosphorylation in the brain of AD animal model including behavioural improvement. But still it is unknown whether the curcumin is directly involved in those processes or enhance those mechanisms. Thus in this review we wa.. Read More»
  DOI: 10.4172/2376-0281.1000274

  Abstract PDF