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Research Article
A Solid and Robust Model for Xylitol Enzymatic Production Optimization
Author(s): Branco R. F, Santos J. C and Silva S.SBranco R. F, Santos J. C and Silva S.S
Xylitol production by fermentation process is widely studied. However, few works describes the enzymatic production of this polyalcohol. This works aims to determine a model that could explain the xylitol enzymatic production as a function of major variables in this process. For this purpose we applied an adequate statistical analysis and response surface methodology (RSM). Initially, variables were selected using a 25-1 fractioned factorial design. Xylose and NADPH concentrations were chosen for the optimization experiments. In order to use the RSM, experiments according to a 22 factorial design with star points and triplicate in the center were carried out. The statistical analysis resulted in a quadratic model which could explain 98.6 % of the volumetric productivity in xylitol in function of xylose and NADPH concentrations. Using predicted expe.. Read More»
DOI:
10.4172/2155-9821.1000108
Journal of Bioprocessing & Biotechniques received 3351 citations as per Google Scholar report