Journal of Clinical & Medical Genomics

Carina Parikh

Publications

• Research Article
  Epigenetics in Clinical Practice: Characterizing Patient and Provider Experiences with MTHFR Polymorphisms and Methylfolate
  Author(s): Erica Oberg, Chris Givant, Briana Fisk, Carina Parikh and Ryan BradleyErica Oberg, Chris Givant, Briana Fisk, Carina Parikh and Ryan Bradley
  
  Background: Observational research associating methylenetetrahydrofolate reductase (MTHFR) polymorphisms with risk of autism, depression, cancer and cardiovascular disease has led to increased diagnoses of MTHFR, however, doctors lack knowledge about safety, effectiveness, and clinical implications of MTHFR treatment. Treatment strategies are hypothetical and mechanistically-based, including methylfolate with or without other B vitamins. Aims: This study was designed to formally describe patient and healthcare provider experiences with the diagnosis and clinical management of MTHFR. Methods: Guided by a structured interview guide, a qualitative study queried patients’ and providers’ observations regarding: testing indications, reaction to results, treatment protocols, and clinical response including adv.. Read More»
  DOI: 10.4172/2472-128X.1000124

  Abstract PDF