Journal of Clinical Case Reports

Chandrakala Magudapathi

Publications

• Case Report
  Glanzmann's Thrombasthenia Complicating Pregnancy
  Author(s): Chandrakala Magudapathi, Suthanthira Kannan and Deepa GiriChandrakala Magudapathi, Suthanthira Kannan and Deepa Giri
  
  Glanzmann’s thrombasthenia is a rare autosomal recessive hemorrhagic disorder caused by abnormal platelet glycoprotein complex (GP IIb-IIIa) presenting with hemorrhagic symptoms. Pregnancy is not uncommon because fertility is not affected but an association is rare. Also delivery often results in haemorrhage. Newborn thrombocytopenia is occasionally severe, but is always transitory. We report a 21-year old primigravida, who underwent vaginal delivery at term with IUGR and Oligohydramnios. Glannzmann’s thrombasthenia was characterized by aggregation and this patient went undiagnosed till adolescence until evaluated for puberty menorrhagia which is uncommon. She received single donor platelet transfusion during the intrapartum period along with tranexemic acid. Platelet transfusion may result in alloimmunization and make successive transfusions less effective. We did not use.. Read More»
  DOI: 10.4172/2165-7920.1000142

  Abstract PDF