Clinical Depression

Charles Harris

Publications

• Research Article
  Attention, Concentration and Planning Ability Improvement in Response to Depression Treatment during Acute Psychiatric Hospitalization
  Author(s): Luba Leontieva, Sergey Golovko, Aadhar Adhlakha, Lyuba Polinkovsky, Charles Harris, Donald A Cibula, Thomas Schwartz and James L MegnaLuba Leontieva, Sergey Golovko, Aadhar Adhlakha, Lyuba Polinkovsky, Charles Harris, Donald A Cibula, Thomas Schwartz and James L Megna
  
  Background: Cognitive symptoms are some of the most distressing for patients who are depressed. The goal was to investigate whether depressed patients’ cognition changed depending on treatment with SSRIs (No-NOR) vs. Norepinephrine-enhancing medications (NOR) during an inpatient stay. Methods: This was an observational, naturalistic, pilot study that used a repeated measures design. 119 depressed inpatients, average age 39 years, 61% females, 77% Caucasian, 74% with mood disorders, 50% Cluster B traits/disorders and 32% psychoactive substance abuse disorders participated. The Trail Making Test (TMT), Hamilton Depression Rating Scale (HDRS), and Outcome Questionnaire-45(OQ-45) were used. Results: Revealed significant differences between admission and discharge in HDRS (MA=24, MD=9, t (98)=25.30, p<0.001), and OQ-45.. Read More»
  

  Abstract PDF