Clinical and Medical Case Reports

Charles O Obonyo

Publications

• Research Article
  Diagnosis and Management of Early-Onset Neonatal Sepsis (Eos) Among High-Risk Neonates in Kisii Teaching and Referral Hospital and Homabay County Referral Hospital, Western Kenya
  Author(s): Jaqueline Mulongo Naulikha, Ondimu Thomas Orindi, Asito Stephen Amollo and Charles O ObonyoJaqueline Mulongo Naulikha, Ondimu Thomas Orindi, Asito Stephen Amollo and Charles O Obonyo
  
  Neonatal sepsis (NS) is the third most common contributor to neonatal deaths worldwide, the majority of which occur within the first 72 hours of life (Early-onset sepsis [(EOS)]). Diagnosis of EOS is challenging due to limitations with blood volume, poor sensitivity of culture, delay in culture results, and most importantly, lack of bacterial blood culture capacity in high burden settings. Current syndromic algorithms for diagnosis of EOS lack validations and are needed to enable clinical decision making for management. To evaluate the diagnostic performance of a severe illness syndromic algorithm in distinguishing culture-proven or probable EOS from unlikely sepsis. Neonates with their mothers with suspected neonatal sepsis that gave a written consent and made the enrollment criteria that fulfilled the WHO case definition of septicemia within the first 72 hours of life were enrolled .. Read More»
  

  Abstract PDF