Antigua
Research Article
First Antiretroviral Therapy Changes in People Living with HIV in Senegal:
Incidence, Causes and Predictive Factors
Author(s): Assane Diouf, Tracie Joyner Youbong, Fatou Lama Dieye, Viviane Marie Pierre Cisse-Diallo, Khardiata Diallo-Mbaye, Moustapha Diop, Maryvonne Maynart, Cheikh Tacko Diop and Moussa SeydiAssane Diouf, Tracie Joyner Youbong, Fatou Lama Dieye, Viviane Marie Pierre Cisse-Diallo, Khardiata Diallo-Mbaye, Moustapha Diop, Maryvonne Maynart, Cheikh Tacko Diop and Moussa Seydi
Introduction: In resource-limited countries, the number of available antiretroviral (ARV) drugs is relatively limited. Hence, caregivers face some caution and constraints in the changes of ARV treatment (ART) in people living with HIV (PLHIV). Our objective was to calculate the incidence, to describe the main causes and to identify the predictive factors of the first change of ARV treatment in Senegal. Methods: We conducted a retrospective cohort study on 331 HIV infected patients who initiated ART in 2009- 2011 and followed until March 2012. The incidence was estimated using Kaplan-Meier method. The causes have been grouped into five categories. The identification of predictive factors was done using a Cox proportional hazards model. Results: At inclusion, mean age, IMC and CD4 cell count were 41 years (interquartile range (IQR)=35-48), 18 kg/ m² (IQR=15.6-21.5) and 92 cells/&.. Read More»
DOI:
10.4172/2155-6113.1000709
Journal of AIDS & Clinical Research received 5264 citations as per Google Scholar report