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Research Article
High Homocysteine Levels are Closely Associated with the Categories of Coronary Artery Diseases as well as Low Status of Folic Acid and Vitamin B12
Author(s): Yan Ma, Duanliang Peng, Chenggui Liu, Huang Chen and Jun LuoYan Ma, Duanliang Peng, Chenggui Liu, Huang Chen and Jun Luo
Background: Homocysteine (Hcy) has been considered as an independent risk factor for coronary artery disease (CAD). Folic acid and vitamin B12 are two vital regulators in Hcy metabolic process. We evaluated the associations between Hcy and the categories of CAD as well as the levels of folic acid and vitamin B12.
Methods: Hcy, folic acid and vitamin B12 from 292 CAD patients, including 73 acute myocardial infarction (AMI), 116 unstable angina pectoris (UAP), 103 stable angina pectoris (SAP), and 100 non-CAD controls were measured, and the data were analyzed by SPSS software.
Results: Hcy concentrations of AMI patients were the highest, and UAP patients were second, and SAP patients were the third higher, which were significantly higher than controls (p<0.01). Compared to SAP patients, patients with AMI and UAP h.. Read More»
DOI:
10.4172/2167-1095.1000228
Journal of Hypertension: Open Access received 614 citations as per Google Scholar report