Maulana Azad Medical College,
New Delhi
India
Case Report
Toxic
Leucoencephalopathy Due to CHOP Therapy in a Patient with
NonHodgkin’s Lymphoma
Author(s): Chetanya Malik, Aditya Kutiyal, Sanjay Pandit, Sandeep Garg and Naresh GuptaChetanya Malik, Aditya Kutiyal, Sanjay Pandit, Sandeep Garg and Naresh Gupta
Toxic leucoencephalopathy is damage to cerebral white matter due to exposure to cranial irradiation, environmental toxins, drugs of abuse and chemotherapeutic agents. It results in wide variety of clinical manifestations like personality change, inattention, memory loss, abulia, stupor, coma and death. It leads to white matter demyelination which is visible on T2 weighted MRI as hyperintensity. We report a rare case of a 14-year-old boy with large B cell lymphoma who developed toxic leucoencephalopathy due to exposure to CHOP regimen.
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DOI:
10.4172/2165-7920.10001006
Journal of Clinical Case Reports received 1345 citations as per Google Scholar report