Research Article
Water Ingestion Reduced Exhaled Nitric Oxide in the Course of the Osmopressor Response
Author(s): You-Hsiang Chu, Herng-Sheng Lee, Shung-Tai Ho, Che-Se Tung, Ching-Jiunn Tseng, Meng-Hung Lee and Chih-Cherng LuYou-Hsiang Chu, Herng-Sheng Lee, Shung-Tai Ho, Che-Se Tung, Ching-Jiunn Tseng, Meng-Hung Lee and Chih-Cherng Lu
Water ingestion induces a robust increase in blood pressure (BP) and vascular resistance in patients with an impaired efferent baroreflex. The mild pressor response was also present in elderly healthy subjects; however, there was no change in arterial blood pressure and notably no change, or even a slight reduction in heart rate in young healthy subjects. Nitric oxide (NO) has emerged as a major regulator mechanism of the cardiovascular system and the stressful situation has been linked to a reduction in serum NO.Thus we hypothesized that the exhaled nitric oxide(eNO) might be feasible to be a biomarker that can aid in the research of the osmopressor responses. The purpose of the present study was to examine whether the non-invasive monitor of eNO could reflect the osmopressor response after water ingestion. In a randomized, controlled, crossover fashion, 34 young healthy subjects (ag.. Read More»
DOI:
10.4172/2167-1095.1000129
Journal of Hypertension: Open Access received 614 citations as per Google Scholar report