Journal of Clinical & Medical Genomics

Chinmoy KP

Publications

• Research Article
  Polymorphisms of Cytochrome P450 2E1 Gene and Gastric Cancer Risk: A Case Control Study from West Bengal, India
  Author(s): Sudakshina G, Soumee G, Bankura B, Sahab ML, Chinmoy KP, Chakraborty S and Das MSudakshina G, Soumee G, Bankura B, Sahab ML, Chinmoy KP, Chakraborty S and Das M
  
  Background: RsaI/PstI and DraI polymorphisms of cytochrome P450 2E1 (CYP2E1) gene are regarded as the most common polymorphisms associated with gastric cancer (GC). Very few data of these polymorphisms have been reported from India with regard to GC risk. We evaluated RsaI: -C1053T (rs2031920), PstI: -G1295C (rs3813867) site in the 5’ flanking region, DraI: T7668A (rs6413432) site in intron 6, -G71T rs6413420 and G4768A or V179I rs6413419 polymorphisms of CYP2E1 with GC risk in the population of West Bengal, India. Methods: We enrolled 105 GC patients (cases) and corresponding sex, age and ethnicity matched normal 108 individuals (controls) for the study. Genotyping for rs6413419, rs6413420, rs6413432, rs2031920, rs3813867 of CYP2E1 was performed using DNA sequencing and RFLP analysis. Results and conclusion: Our.. Read More»
  DOI: 10.4172/2472-128X.1000148

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