Medicinal Chemistry

Christian Agyare

Publications

• Research Article
  In vitro Activity and Evaluation of Quality of Some Selected Penicillins on the Ghanaian Market using Developed HPLC Methods
  Author(s): Rita Frema Boadu, Christian Agyare, Martin Adarkwa-Yiadom, Francis Adu, Vivian Etsiapa Boamah and Yaw Duah BoakyeRita Frema Boadu, Christian Agyare, Martin Adarkwa-Yiadom, Francis Adu, Vivian Etsiapa Boamah and Yaw Duah Boakye
  
  The use of antibioticsin health delivery is inevitable since it is one of the most prescribed medications. The quality and efficacy of these medications are crucial in health systems since they can affect the quality of healthcare delivery. The study was designed to determine the quality and activity of some penicillins on the Ghanaian market. A total of 54 samples (29 capsules and 25 suspensions) of different brands and batches were collected from different pharmacies in Accra and Kumasi, Ghana, from October 2011 to May 2012. The activity (zones of inhibition) and minimum inhibitory concentration (MIC) of the samples were determined by the agar-well diffusion and micro-dilution methods respectively against two typed strains of Gram-negative and Gram-positive bacteria. Quality of the samples was determined quantitatively by developed and validated HPLC.. Read More»
  DOI: 10.4172/2161-0444.1000235

  Abstract PDF