Journal of Clinical Anesthesiology: Open Access

Christoph Schramm

Publications

• Research Article
  The Association of Blood Cholinergic Esterases and Other Risk Factors on the Development of Postoperative Delirium
  Author(s): Konstanze Plaschke, Sara-Susan Schulz, Jürgen Hoffmann, Markus A Weigand, Thomas Bruckner, Christoph Schramm and Jürgen KopitzKonstanze Plaschke, Sara-Susan Schulz, Jürgen Hoffmann, Markus A Weigand, Thomas Bruckner, Christoph Schramm and Jürgen Kopitz
  
  Study Objective: Delirium is an important complication after surgical intervention. One of the potential risk factors for cognitive disorders is deterioration in cholinergic neurotransmission including anticholinergic medications. We hypothesize that changes in blood cholinesterases (CHE) are associated with postoperative delirium. Design: Prospective cohort study. Setting: Postoperative delirium was assessed at least once daily in all included patients (n=103) preoperatively and on the first and third postoperative day during their stay on the intensive care unit (ICU) or in hospital. Patients: undergoing a surgery on the head were included. Interventions and Measurements: Postoperative delirium was assessed using the Intensive Care Delirium .. Read More»
  

  Abstract PDF