Cardiovascular Diseases & Diagnosis

Christoph Thomssen

Publications

• Research Article
  Natriuretic Peptides and Troponin I Do Not Predict Chemotherapy-Induced Cardiac Toxicity
  Author(s): Katja Jungandreas, Alexander Vogt, Wieland Voigt, Karin Jordan, Hans-Georg Strauß, Christoph Thomssen, Henning Ebelt, Karl Werdan, Jürgen Schwamborn and Axel SchlittKatja Jungandreas, Alexander Vogt, Wieland Voigt, Karin Jordan, Hans-Georg Strauß, Christoph Thomssen, Henning Ebelt, Karl Werdan, Jürgen Schwamborn and Axel Schlitt
  
  Background/Aims: Cytostatics and human antibodies are successfully being used to treat oncological diseases. Despite the beneficial effects of these potent drugs, cardiotoxicity represents one of the most relevant side effects and limits their usage. It is very important to detect cardiotoxicity at an early stage particular in patients under curative chemotherapy to avoid long-term side effects and impairment of quality of life. The aim of this prospective study was to investigate the value of natriuretic peptides and troponin for early detection of cardiotoxicity. Patients and Methods: In this single-center study, 99 cancer patients under treatment with anthracyclines, taxanes, and/or trastuzumab were prospectively included. Clinical examination, echocardiography, and blood sampling (brain natriuretic peptide (BNP), N-terminal-proBNP, and t.. Read More»
  DOI: 10.4172/2329-9517.1000140

  Abstract PDF